Defending champions FC Porto take on English Premier League leaders Manchester City, while their city rivals Manchester United face Ajax Amsterdam. The other English entrant left Stoke City have to take on the mighty FC Valencia, while Lazio Roma have been paired with Atletico Madrid. In a low country derby AZ Alkmaar take on Belgian giants RSC Anderlecht.

The Round of 32 matches will be played on February 16 and 23, while the Round of 16 games are scheduled to take place on March 8 and 15.

The Fixtures

Round of 32FC Porto – Manchester CityAFC Ajax Amsterdam – Manchester UnitedFC Lokomotiv Moscow – Athletic BilbaoRedBulls Salzburg – Metalist KharkivStoke City – FC ValenciaRubin Kasan – Olympiacos PiräusAZ Alkmaar – RSC AnderlechtSS Lazio Roma – Atletico MadridSteaua Bucharest – FC Twente EnschedeViktoria Plzen – FC Schalke 04Wisla Krakau – Standard LiegeSporting Braga – Besiktas IstanbulUdinese Calcio – PAOK SalonikiTrabzonspor AS – PSV EindhovenHannover 96 – FC BruggeLegia Warsaw – Sporting Lisboa

Round of 16Salzburg/Metalist – Rubin/OlympiacosLegia/Sporting – Porto/Manchester CitySteaua/Twente – Plzen/SchalkeWisla/Standard – Hannover/Club BruggeStoke/Valencia – Trabzonspor/PSVAZ/Anderlecht – Udinese/PAOKLazio/Atlético – Braga/BesiktasAjax/Manchester United – Lokomotiv/Athletic

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